A simple, sensitive and economical non extractive spectrophotometric (colorimetric) method has been developed for the quantitative determination of Olanzapine from Pharmaceutical tablet dosage form. Developed method is based on formation of ion pair colored complex of drug with Thymol Blue Dye. The formed complex in Methylene Chloride solvent does not require any extraction and showed absorbance maxima at 272.0 nm. Linearity was observed in concentration range of 0-10 µgm/ml of Olanzapine. The results of analysis were validated statistically and by recovery studies.
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